I have the same problem since after rebuilt the postfix. Found the solution by myself. Make sure the /var/lib/clamav & /var/log/clamav with the right user & group. chown -R clam:clam /var/lib/clamav chown -R clam:clam /var/log/clamav Open the file /etc/freshclam.conf and make sure the lines are set to as below: DatabaseDirectory…